405TS / LS

The 405 TS Microplate Washer is #1 in life science research, known for its excellent performance and outstanding reliability.  The 405 TS has a unique set of features designed to efficiently, effectively wash cell-based assays, microsphere-based assays and ELISA, with outstanding results for every application.  The patented Verify™ technology automatically checks for manifold tube blockages before a wash cycle, and Ultrasonic Advantage™ automatically cleans any blocked manifold tubes. These functions save time and frustration, and ensure successful results.
The 405™ LS Microplate Washer is the fifth generation BioTek washer, known for superior performance and reliability for washing protocols ranging from gentle cell washing to vigorous ELISAs. The 405 LS has a simple user interface for creation and execution of wash, dispense, aspirate and maintenance protocols within the extensive onboard software. For use under computer control, BioTek’s LHC™ Software is available in standard and 21 CFR Part 11 compliant versions. The optional BioStack™ is available for walk-away automation of up to 50 microplates.

Typical Applications:

  • Bead washing
  • Cell washing /media exchange

  • Automating the Wash Steps of ELISpot Assays using BioTek’s 405 TS Microplate Washer

    Enzyme-linked immunospot (ELISpot) assays are a flexible and powerful tool for investigating secreted molecules from whole cells, particularly for analyzing the immunological functions and responses of peripheral and lymphoid white blood cells. Here we describe a convenient and effective method for automating the most tedious aspects of conducting ELISpot assays using the versatile 405™ TS Microplate Washer.

    Instrument: 405 TS, 405 LS

  • Plaque Assay

    A cell monolayer is treated with a dilution of a GFP-expressing virus. The cells are then coated with agar, which limits the virus spread to only neighboring cells.After incubation, GFP+ circles of infected cellsare counted for virus titration.

    Related Instruments: Cytation 1Cytation 5, Cytation 7Lionheart FXLionheart LX405 TS, 405 LS

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