Drugs of Abuse
Whether working with drugs of abuse, pharmacokinetics or trace residues from a crime scene, confidence in the analytical results is critically important.
We, offer analytical instruments, automated sample preparation solutions and consumables for a wide variety of applications including drugs of abuse, trace residues analysis, medicinal pharmacology, new born screening (NBS) tests, immunosuppressive drugs, organic acid and heavy metal analysis, and more.in collaboration with Shimadzu and our other partners.
Drugs of Abuse
Trace Residues
Explosives
Toxicology and doping
Therapeutic Drug Monitoring (TDM)
Metabolomics, Genomics, Proteomics
Newborn Screening (NBS)
Immunosuppressive Drugs
Heavy Metals
This procedure describes the method of electrothermal atomic absorption to be used to determine the amount of nickel in AA in whole blood and urine samples.
Instrument: Shimadzu AA-7000
Povidone (polyvinylpyrrolidone, PVP) is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs. It additionally acts as a disintegrant and tablet binder.
The revision to the harmonized standard for Povidone has been approved and Formic Acid in Povidone is now required to be measured.
Particularly in judicial cases, the amount of alcohol and foreign substances in the human blood should be calculated as promil. The purpose of this study is to analyze the blood alcohol level using a gas chromatograph and headspace method.
Instrument: Shimadzu GC-2010 Plus Gas Chromatograph with Headspace Unit (GC-HS)
In this application bulletin, examples of analysis of paint residues on board chip and automobile coatings using an infrared microscope.
Instrument: IRTracer-100, AIM-9000
Qualitative and quantitative analysis of Ceramide and Sifingomyelin substances in human plasma and rat liver.
Instrument: LCMS-8040 Liquid Chromatography Mass Spectrometer (LCMSMS)
Measurement of Adenosine content in tissue transplantation in plastic surgery
Instrument: LCMS-8040 Liquid Chromatography Mass Spectrometer (LCMSMS)
L-FABP protein is normally a protein involved in the intracellular transport of long-chain fatty acids in kidney proximal tubules. L-FABP has a role in confirming renal ischemic damage and nephrotoxic injury. Damage procedures can be observed at certain hours after transplantation.
Instrument: LCMS-8040 Liquid Chromatography Mass Spectrometer (LCMSMS)
Oliver Carney, BMG LABTECH Ltd, Aylesbury, UK; Kelly Moffitt and Charlene Robb, ProAxsis, Belfast, Northern Ireland, 02/2016
The neutrophil elastase is a biomarker of respiratory diseases such as cystic fibrosis (CF) or chronic obstructive pulmonary disease (COPD). A simple, rapid and accurate test for neutrophil elastase levels in patient samples would be a significant medical benefit. Established methods do not specifically verify the presence of the enzyme leading to a high value of false positives. In this application note we show how to use the ProteaseTag™ Active Neutrophil Elastase Immunoassay from the company ProAxsis which is based in Northern Ireland.
The assay uses tags to specifically bind the enzyme of interest. Chromogenic detection is performed with the CLARIOstar® microplate reader which analysis the results and return qualified data automatically.
Protease levels can be determined in sputum sol, bronchoalveolar lavage, wound exudate or serum free cell culture.
Structural analysis of kidney stones with FTIR spectrophotometer
Instrument: Shimadzu IRAffinity-1s Fourier Transform Infrared Spektrofotometre
Forensics/Toxicology and more...
PAH (Polycyclic Aromatic Hydrocarbon) analysis in drinking water
Instrument: LC-20A Prominence (HPLC)