Thermo Fisher Scientific Gibco™ ExpiCHO™ Stable Production Medium (SPM) is specifically designed to simplify your cell line development process into production with minimal effort and a high degree of confidence. This chemically defined, protein-free, animal origin component-free formulation is fully optimized for large-scale fed-batch culture with ExpiCHO-S cells. ExpiCHO SPM supports an easy transition from transient to stable production, provides high titers without the need for additional medium optimization (see figures below), and works well with existing EfficientFeed C+ supplement.
ExpiCHO SPM is part of the ExpiCHO family, an end-to-end solution that empowers you to carry out your entire workflow from transient to stable expression without having to screen or optimize media and feeds.
Simplify your process as you transition into stable clones with ExpiCHO™ SPM—no cell adaptation, no media optimization, no changes in cell doubling time and peak density. ExpiCHO™ SPM eases the transition using ExpiCHO-S cells and provides optimal performance with less need for fine-tuning from development scientists to get you to the next step faster. This medium supports high titers under standard fed-batch process conditions in conjunction with EfficientFeed C+ supplement. It is available in liquid format (this page) or in our AGT dry format from 10 L through 450 L equivalents with larger sizes available upon request.
The ExpiCHO™ family includes products that are engineered to work seamlessly with each other. ExpiCHO™ SPM is a member of this family and allows expanded support of bioproduction from transient to stable protein expression. Look for ExpiCHO-branded protocols and methods to get optimal performance in the development process.
ExpiCHO™ SPM liquid format and AGT dry format demonstrate comparable cell growth and titer performance. Therefore, scale-up and manufacturing using AGT dry format is simplified by knowing that the reconstituted AGT dry format will behave similarly to the liquid format used prior to scale-up. The AGT dry format is easy to reconstitute; just add water and it will automatically adjust pH and osmolality. This can help provide efficiencies in supply chain complexity, reconstitution complexity, and, therefore, overall expense.
• ExpiCHO™ Stable Production Medium (this page)
• ExpiCHO™ Expression Medium
• ExpiCHO-S cells
• Expifectamine CHO Transfection Kit
Loading...
Think big see beyond... Ant Teknik is is offering sales, service and spare part supply; validation, application and training as well your turn-key laboratory project services for research and QC laboratories...
What is m/z? what does S/N ratio mean? What does is included in OQ? Explore answers to the most common questions we get from analysts…
Tips from our experts on chromatography, spectroscopy and sample preparation that you can benefit from in analytical laboratory...
