Growing needs for higher work efficiency and a more flexible working style are changing patterns regarding LC analysis. It's high time for HPLC (high performance liquid chromatography) that requires less analyst intervention and delivers robust and reliable results. The new, integrated i-Series LC (liquid chromatography) system combines the excellent performance of previous HPLC models with automation efficiency.
Innovative - Remote device operation and monitoring allows analyzes to be performed remotely, reducing time spent in the lab.
Intelligent - Software integration provides both data reliability and improved business efficiency.
Intuitive - The intuitive operation ensures an efficient workflow.
It is an ideal system for synthetic compound analysis and quantification with standard procedures.
The system is suitable for many different applications such as pharmaceutical, chemical, food and environmental. It can be used alone or within a network. The minimum space it occupies facilitates the use and transport of the systems. There are three types of detectors (UV, PDA, no detector) available to suit your analysis methods and objectives. There are also models with oven cooling function (C model) and without cooling.
It is the ideal UHPLC system for multiple analyte analysis such as drug dissolution tests. The autosampler of the system has a total capacity of 216 standard vials and has a direct access mechanism where the user can add samples even during analysis. It is a UHPLC (ultra performance chromatography) model suitable for 700 bar operation. The method transfer system provides excellent support for running UHPLC and HPLC methods in a single instrument.
Automated support functions using digital technology such as M2M, IoT and Artificial Intelligence (AI) to ensure higher productivity and maximum reliability.
It allows a system to monitor and diagnose itself, handle any issues during data collection without user input, and automatically pretend to be run by an expert.
It supports the retrieval of high quality, reproducible data for both routine and demanding applications, regardless of the user's skill level.
Analytical Intelligence functions, such as FlowPilot and mobile phase monitoring, and LabSolutions™ Direct chromatography software can provide an automated workflow together with remote operation and monitoring from instrument startup to analysis completion.
Automated workflows incorporate the work-style habits of experienced analysts. The result is reliable data collected over extended periods.
Using Networks for More Improvements in Work Efficiency
LabSolutions CS chromatography software allows remote operation and monitoring of all instruments on the analytical network from any locations, even from home. Analysis data and reports are managed on a centralized database where administrative authorization allows managers to assign appropriate operational restrictions to operators, depending on their expertise and rank.
Making sure you have sufficient mobile phase in the system—before batch analysis—is critical to keeping your lab running smoothly. If you run out of mobile phase mid-batch, you have to stop the batch and take corrective action, resulting in costly workflow delays and potential loss of samples.
To overcome this challenge, the Mobile Phase Monitor enables real-time, gravimetric monitoring of mobile phase levels to ensure maximum uptime. Levels for mobile phase or autosampler rinse solution may be monitored in up to six containers. A large bottle version is also available. The containers can also be checked remotely from a smart device (PC/iOS/Android).
UHPLC chromatography columns can be damaged by sudden pump starts and extreme gradient changes, especially true with polymeric packings. Smart Flow Control (FlowPilot) increases the flow rate gradually to the method set point according to the status of the column oven, extending the life of your columns.
Using LabSolutions Direct, analysts can operate instruments remotely and implement pre-configured methods and batch analyses using the web browser of a computer or a smart device. Instrument status and chromatograms can also be monitored remotely to reduce the time and labor required to travel to and from the laboratory for improved work efficiency.
The manual integration of un-resolved peaks is a labor-intensive process and prone to inconsistent results depending upon the experience level of the user. Shimadzu’s proprietary i-PeakFinder peak integration algorithm is perfect for such situations. i-PeakFinder processes large volumes of data with high precision in a single step, saving a lot of time and increasing the consistency of results.
Aynı kromatogramı elde ederken bir test yöntemini (analitik koşullar veya yöntem) bir cihazdan diğerine geçirmek zorlu bir süreç olabilir.
i-Serisi, sistem uyumluluğunu ve veri tekrarlanabilirliğini sağlamak için önceki Shimadzu sistemleri ve rakip sistemlerle aynı dahili sistem hacimlerinde tasarlanmıştır.
Analitik Koşul Transferi ve Optimizasyon (ACTO) işlevi de gradyan başlangıç zamanını otomatik olarak ayarlar, böylece analistler gradyan analizi ile elde edilen ayrımlarda kolayca ayarlamalar yapabilir.
The i-PDeA II peak deconvolution function uses a multivariate curve resolution alternating least squares (MCR-ALS) method to enable qualitative and quantitative analysis of peaks not fully separated by the column. The i-PDeA II can also be used to check the purity of target peaks. (Only available when using a PDA detector and LabSolutions.)
An auto-validation function means anyone can follow a set procedure and verify the instrument condition easily. The auto-validation function examines solvent delivery stability, wavelength accuracy, absorbance accuracy, gradient accuracy, the presence of any drift/noise, and other parameters. Also, an instrument check function automatically carries out the routine inspections performed before instrument operation and creates a report showing system self-diagnostic results along with a record of consumables usage, including total solvent volume delivered by the delivery pump, total number of injections performed by the autosampler, and the number of hours the lamp has been illuminated. The system check function also manages auto-validation results, making it easy to accurately determine the operating status of the instrument.
Ayrıca, bir cihaz kontrol işlevi, cihaz çalıştırılmadan önce gerçekleştirilen rutin incelemeleri otomatik olarak gerçekleştirir ve sarf malzemeleri kullanımının bir kaydı ile birlikte sistemin kendi kendine teşhis sonuçlarını gösteren bir rapor oluşturur. İletme pompası tarafından verilen toplam solvent hacmini, lambanın aydınlatıldığı saat sayısını ve otomatik örnekleyici tarafından gerçekleştirilen toplam enjeksiyon sayısını içerir.
Sistem kontrol işlevi ayrıca otomatik doğrulama sonuçlarını yöneterek, cihazın çalışma durumunu doğru bir şekilde belirlemeyi kolaylaştırır.
The automatic report generation function in LabSolutions automatically compiles analytical results and presents the data in pre-prepared report templates. This function not only reduces the work associated with report generation, but also avoids errors and data manipulation associated with manual entry and generates well-crafted reports.
By setting up a network environment, reports can be generated, checked and approved from anywhere.
The direct access mechanism on the sample racks allows the user to place the sample on racks not involved in sample injection, even during analysis. In addition, racks can be shared by multiple analysts without interrupting the analysis of samples placed by others. In general, this function improves work efficiency.
By reading a QR Code® displayed on the touch panel, the user is directed to a website with maintenance instructional videos.
This feature helps improve system availability and increases productivity.
The user interface replicates the system flow channel and is used to visually check the operating status of the system.
Method editing can also be performed from the same screen. Thanks to its intuitive design, even users who are completely new to liquid chromatography can navigate the user interface with minimal training.
In addition to the temperature control function for flow cells, the i-Series uses new temperature control technology for detector optics known as TC-Optic (Temperature Controlled Optics).
This provides a more stable baseline that is less sensitive to room temperature variation and higher sensitivity during confirmatory testing and quantitative testing of trace components.
Shimadzu's proprietary flow channel design, parts and materials reduce the carry-over effects of sample residue to almost zero.
The ultra-low carry-through performance has been improved to 0.0025% (chlorhexidine, assigned conditions), providing highly accurate quantitative performance when analyzing complex samples.
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